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    Cocoa Flavanols

    Cocoa flavanols are a class of polyphenolic compounds naturally present in cacao beans, the raw ingredient behind chocolate and cocoa powder. Processing methods like roasting and alkalization significantly reduce flavanol content, so minimally processed cocoa or standardized extracts deliver the highest concentrations. They are among the most well-studied dietary polyphenols, with robust evidence linking regular intake to cardiovascular and cognitive benefits.

    Research Evidence
    May support skin health through improved microcirculation
    Limited
    Reduces blood pressure modestly in adults
    Strong
    Potential benefits for insulin sensitivity and glucose metabolism
    Limited
    Improves blood vessel dilation and endothelial function
    Strong
    May reduce risk of cardiovascular events with regular intake
    Moderate
    Supports cognitive performance and cerebral blood flow
    Moderate

    Expert Evidence

    4 references from 2 experts

    Currently takes

    “Recently I started eating roasted raw cacao beans for their polyphenol content. I actually like the bitterness. They have a lot of fiber.”

    Health Effects & Risks of Kratom, Opioids & Other Natural Occurring Medicines | Dr. Chris McCurdy

    2:02:44
    Andrew Huberman

    2 references in 2 episodes from 2025

    AI-generated summary

    Huberman has recently added roasted raw cacao beans to his routine, citing their polyphenol content and high fiber as reasons. He notes a personal preference for their bitter taste. No specific dosing, brand recommendations, or cautions are discussed.

    Currently takes

    “CocoaVia, I'm taking the cardio, the heart one, and I take the recommended dose.”

    This Is Everything Rhonda Patrick Supplements With

    0:53
    Rhonda Patrick

    2 references in 2 episodes from 2024–2025

    AI-generated summary

    Rhonda Patrick takes CocoaVia (the cardio/heart formula) at the recommended dose, consuming it with lunch in the afternoon. She confirms personal use but does not discuss specific dosing numbers, health benefits, or any cautions.

    2025
    2024
    Safety & Cautions

    Side Effects

    • Mild digestive discomfort at high doses
    • Caffeine-related effects (jitteriness, insomnia) from cocoa sources
    • Headache in sensitive individuals
    • Potential for added sugar and calorie intake from chocolate forms
    Cocoa flavanols are generally well-tolerated at typical supplemental doses. Those sensitive to caffeine or theobromine should start with lower amounts, and people taking blood pressure medications should monitor levels since flavanols may have an additive blood-pressure-lowering effect.
    Pairs Well With
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