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    CoQ10

    Evening with food

    Coenzyme Q10 is a fat-soluble compound produced naturally in every cell of the body, where it plays a critical role in mitochondrial energy production. Found in highest concentrations in energy-demanding organs like the heart, liver, and kidneys, endogenous CoQ10 levels decline significantly with age and with statin use. It exists in two forms — ubiquinone (oxidized) and ubiquinol (reduced) — both widely available as supplements.

    Research Evidence
    May support blood pressure reduction in hypertensive individuals
    Moderate
    Offsets CoQ10 depletion caused by statin medications
    Strong
    May improve exercise performance and reduce fatigue
    Limited
    Provides antioxidant protection against lipid peroxidation
    Moderate
    Supports cardiovascular function and may improve heart failure symptoms
    Strong
    Reduces frequency of migraine headaches
    Moderate
    Safety & Cautions

    Side Effects

    • Mild nausea
    • Digestive discomfort
    • Insomnia if taken late in the day
    • Decreased appetite
    CoQ10 is generally well-tolerated even at higher doses. Those on blood-thinning medications (especially warfarin) should consult a healthcare provider, as CoQ10 may reduce anticoagulant efficacy.
    Pairs Well With
    Price Comparison
    From $0.17/ct
    Z
    ZEBORABest Value
    4.7
    120 ct

    $0.17/ct

    $19.99 total

    N
    Nutricost
    4.5
    120 ct

    $0.21/ct

    $24.95 total

    Q
    Qunol
    4.6
    100 ct

    $0.33/ct

    $32.99 total

    L
    Leaping Lynx
    4.6
    60 ct

    $0.30/ct

    $17.94 total

    N
    NOW Foods
    4.7
    60 ct

    $0.45/ct

    $27.14 total

    L
    Life Extension
    4.6
    60 ct

    $0.51/ct

    $30.38 total

    P
    Pure Encapsulations
    4.7
    60 ct

    $1.58/ct

    $95.00 total