Fadogia Agrestis
Fadogia agrestis is a shrub native to West Africa, traditionally used in Nigerian folk medicine as an aphrodisiac and vitality enhancer. It has gained popularity in the supplement space primarily for its potential to support healthy testosterone levels through stimulation of luteinizing hormone (LH) production.
Expert Evidence
4 references from 1 expert
“I've been taking fadogia for some period of time. All my markers and tests indicate that there's no toxicity. But I've been taking 600 milligrams per day, cycling it for about 8 to 12 weeks on and then a few weeks off.”
Tools for Hormone Optimization in Males | Dr. Kyle Gillett
1:25:344 references in 4 episodes from 2022–2025
Huberman takes 600mg of fadogia agrestis daily, cycling 8-12 weeks on and a few weeks off, reporting increases in LH, testosterone, and free testosterone without estrogen issues or LH down-regulation upon cycling off. He states his blood work shows no toxicity. No third-party research is cited and no cautions beyond his personal cycling protocol are discussed.
Side Effects
- Potential testicular toxicity at high doses (animal data)
- Possible changes in liver enzymes
- Gastrointestinal discomfort
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