Hydroxyapatite
With meals
Hydroxyapatite is the primary mineral component of human bones and teeth, consisting of calcium and phosphorus in a crystalline lattice structure. As a supplement, microcrystalline hydroxyapatite (MCHA) provides calcium in a form that closely mirrors the body's own bone mineral, along with trace amounts of phosphorus, collagen, and growth factors. It has been studied as an alternative to conventional calcium salts for supporting skeletal integrity.
Research Evidence
Supports dental enamel remineralization
LimitedSupports bone mineral density maintenance in postmenopausal women
ModerateProvides bioavailable calcium with lower GI side effects than calcium carbonate
ModerateDelivers bone matrix proteins and growth factors alongside calcium
LimitedMay slow bone loss comparably to or better than calcium carbonate
ModerateSafety & Cautions
Side Effects
- Mild constipation
- Bloating or gas
- Nausea at higher doses
- Hypercalcemia with excessive intake
Hydroxyapatite is generally well-tolerated and tends to cause fewer digestive side effects than calcium carbonate. Those with kidney disease, hypercalcemia, or a history of kidney stones should consult a physician before supplementing, and sourcing matters — choose products tested for heavy metal contamination since MCHA is derived from bovine bone.
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