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    Multivitamin

    A multivitamin is a dietary supplement that combines essential vitamins and minerals into a single dose, typically including vitamins A, C, D, E, K, B-complex vitamins, and key minerals such as zinc, magnesium, and selenium. Designed to serve as a broad-spectrum micronutrient insurance policy, multivitamins help fill nutritional gaps that commonly arise from modern dietary patterns, soil depletion, or increased physiological demands during periods of stress, aging, or intense physical activity.

    Research Evidence
    Fills common micronutrient gaps in typical Western diets
    Strong
    May reduce cancer risk with long-term daily use
    Limited
    Supports immune function through zinc, vitamin C, and vitamin D
    Moderate
    Reduces homocysteine levels through B-vitamin provision
    Moderate
    Supports cognitive function and may slow age-related cognitive decline
    Moderate

    Expert Evidence

    25 references from 4 experts

    Currently takes

    “For me, I also take Micro Vitamin which is the low-dose multivitamin and mineral that I designed and personally use. I designed it to make sure that we don't mega-dose. Most multivitamins on the market mega-dose these micronutrients, which is not ideal. We want to hit our recommended daily intakes but we don't want to exceed them too much because we can cause side effects.”

    Does Lowering Cholesterol Cause Dementia?

    6:53
    Brad Stanfield

    19 references in 15 episodes from 2023–2025

    AI-generated summary

    Brad Stanfield actively takes and designed his own low-dose multivitamin (MicroVitamin), primarily motivated by the COSMOS study findings showing cognitive benefits equivalent to ~2 years less brain aging. He emphasizes multivitamins should complement—not replace—a healthy diet, and warns against mega-dosing. No cautions, reasons to stop, or recommendations against use were discussed.

    Consumption

    He takes MicroVitamin, a low-dose multivitamin and mineral supplement he personally designed, as part of his daily routine alongside creatine and TMG in a combined powder form.

    Benefits

    He highlights the COSMOS study findings showing that daily multivitamin supplementation over 2-3 years improved global cognition, memory, and executive function in older adults, with effects equivalent to slowing brain aging by approximately 1.8-2 years.

    Best Practices

    He stresses that multivitamins should not replace a healthy diet and exercise but serve as a top-up to reach recommended daily intakes, particularly for B vitamins, vitamin D3, K2, magnesium, and zinc, while avoiding mega-dosing common in most commercial multivitamins.

    Currently takes

    “I'm taking the One multivitamin by Pure Encapsulations.”

    This Is Everything Rhonda Patrick Supplements With

    0:34
    Rhonda Patrick

    2 references in 2 episodes from 2024–2025

    AI-generated summary

    Rhonda Patrick takes the Pure Encapsulations One multivitamin daily with lunch. She confirms personal use but provides no specific reasoning for choosing this product, no dosing guidance beyond the standard serving, and no discussion of benefits, cautions, or evidence supporting multivitamin supplementation.

    Currently takes

    “I take a multivitamin with my first meal of the day just to cover any basis that I might be missing out on.”

    Andrew Huberman's Longevity Routine (supplements, diet, peptides, and exercise regimen)

    9:11
    Andrew Huberman

    1 reference in 1 episode from 2024

    AI-generated summary

    Huberman takes a multivitamin with his first meal of the day as nutritional insurance to cover potential dietary gaps. No specific brand, dosage details, or scientific rationale is provided, and no cautions or benefits beyond general coverage are discussed.

    Discusses

    “In our experience, if homocysteine is above 9 to 10 we're looking very seriously at other things. You'd be surprised how many have an omega-3 index under 5. This is why you see in those folks a little bit of basic multivitamin and omega-3 support and all of a sudden the brain fog is gone, the decline just disappears from these people really quickly.”

    Dr. Tommy Wood: Enhancing Brain Performance & Preventing Dementia

    30:06
    Andy Galpin

    3 references in 2 episodes

    AI-generated summary

    Galpin recommends basic multivitamin supplementation alongside omega-3s for individuals with low omega-3 index (under 5) or elevated homocysteine (above 9-10), reporting that this combination can quickly resolve brain fog and cognitive decline. He does not discuss personal use, specific multivitamin dosing, brand preferences, or cautions.

    Safety & Cautions

    Side Effects

    • Mild nausea when taken on an empty stomach
    • Digestive discomfort or upset stomach
    • Metallic taste from iron-containing formulas
    • Bright yellow urine from B-vitamin excretion
    Multivitamins are generally well-tolerated at standard doses, but individuals taking prescription medications should check for interactions, particularly with blood thinners (vitamin K) or thyroid medications (calcium, iron). Avoid stacking a multivitamin with additional single-nutrient supplements without reviewing total intake to prevent exceeding upper limits.
    Pairs Well With
    Price Comparison
    From $0.12/ct
    N
    NutricostBest Value
    4.6
    120 ct

    $0.12/ct

    $14.95 total

    L
    Life Extension
    4.5
    120 ct

    $0.16/ct

    $19.13 total

    N
    NOW Foods
    4.5
    90 ct

    $0.19/ct

    $17.29 total

    T
    THORNE
    4.6
    180 ct

    $0.42/ct

    $76.00 total

    M
    MicroVitamin
    4.7
    30 ct

    $1.97/ct

    $59.00 total