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    Probiotics

    With meals

    Probiotics are live beneficial microorganisms, primarily bacteria and yeasts, that support health when consumed in sufficient quantities. Found naturally in fermented foods like yogurt, kefir, and sauerkraut, they are also available as concentrated supplements containing specific bacterial strains. Different strains serve distinct functions, making strain selection important for targeted health goals.

    Research Evidence
    May help preserve muscle mass alongside dietary interventions after bariatric surgery
    Limited
    Reduces duration and severity of antibiotic-associated diarrhea
    Strong
    Supports immune function and reduces incidence of upper respiratory infections
    Strong
    Influences mood and cognitive function through the gut-brain axis
    Limited
    Improves symptoms of irritable bowel syndrome
    Moderate
    May reduce severity of eczema in children when used preventively
    Moderate

    Expert Evidence

    3 references from 2 experts

    Currently takes

    “I do believe in probiotics. I take probiotics. But there are studies that show that if you take lots and lots of certain probiotics like lactobacillus and you really ramp up the levels, there are things like brain fog that can come from that.”

    How Foods & Nutrients Control Our Moods | Huberman Lab Essentials

    23:11
    Andrew Huberman

    2 references in 2 episodes from 2021–2025

    AI-generated summary

    Huberman takes probiotics and believes in their value, noting the gut microbiome communicates with the brain and can influence mood through neurotransmitter pathways. However, he cautions that excessive intake of certain strains like lactobacillus can cause brain fog. No specific brand, dosage, or timing guidance is provided.

    Currently takes

    “VSL#3 is the probiotic that I take. The sachets have 450 billion, which is more than what the capsules have. 450 billion is like 10 times more than what most probiotics have.”

    Tim Ferriss on Ketosis, Microbiome, Lyme Disease, and Biomarkers

    44:15
    Rhonda Patrick

    1 reference in 1 episode from 2015

    AI-generated summary

    Rhonda Patrick takes VSL#3 probiotic, specifically the sachet form with 450 billion CFU, which she notes is about 10 times more than most probiotics. No specific benefits, timing guidance, or cautions were discussed.

    2025
    2021
    2015
    Safety & Cautions

    Side Effects

    • Mild bloating or gas during initial use
    • Temporary changes in bowel habits
    • Brain fog at very high doses of certain lactobacillus strains
    • Rare allergic reactions to carrier ingredients
    Probiotics are generally well-tolerated by most healthy adults, though immunocompromised individuals should consult a healthcare provider before use. Starting with a lower dose and gradually increasing can minimize initial digestive adjustment symptoms.
    Pairs Well With
    Price Comparison
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