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    Quercetin

    Varies

    Quercetin is a naturally occurring flavonoid abundant in onions, apples, capers, and dark berries. It has gained significant research attention for its antioxidant and anti-inflammatory properties, and more recently for its potential role as a senolytic compound that helps clear damaged, non-dividing cells from the body.

    Research Evidence
    May improve endothelial function and blood pressure
    Moderate
    Supports antioxidant defense against oxidative stress
    Strong
    May lower uric acid levels
    Limited
    Reduces markers of systemic inflammation
    Moderate
    Selectively clears senescent cells when used in senolytic protocols
    Moderate

    Expert Evidence

    3 references from 1 expert

    Previously took

    “Quercetin may lower uric acid levels, but that's not why I personally use quercetin. I use it five days every month to help with the senolytic effect, where I'm trying to clear away old cells that are no longer dividing.”

    Uric Acid & Dementia Cure: Hype or Hope?

    6:47
    Brad Stanfield

    3 references in 3 episodes from 2022–2023

    AI-generated summary

    Brad Stanfield previously took quercetin but stopped, stating current research shows no benefit beyond placebo. However, he also describes using quercetin 5 days per month as a senolytic to clear senescent cells, citing a pilot study showing dasatinib plus quercetin reduced senescent cell burden within 11 days. No specific dosage, brand, or cautions are discussed.

    2023
    2022
    Safety & Cautions

    Side Effects

    • Headache
    • Stomach upset or nausea
    • Tingling in extremities at high doses
    Quercetin is generally well-tolerated at standard doses. However, it may interact with certain antibiotics and blood-thinning medications, so those on prescription drugs should consult a healthcare provider before supplementing.
    Pairs Well With
    Price Comparison
    From $0.07/ct
    D
    DEAL SUPPLEMENTBest Value
    4.7
    300 ct

    $0.07/ct

    $21.99 total

    N
    NatureBell
    4.6
    240 ct

    $0.12/ct

    $27.99 total

    N
    NOW Foods
    4.5
    120 ct

    $0.15/ct

    $17.99 total

    A
    Amazing Nutrition
    4.7
    120 ct

    $0.17/ct

    $20.99 total

    A
    aSquared Nutrition
    4.6
    180 ct

    $0.18/ct

    $32.95 total

    B
    B'LEAF NATURE
    4.5
    120 ct

    $0.31/ct

    $36.75 total

    P
    Pure Encapsulations
    4.8
    120 ct

    $0.42/ct

    $50.50 total

    T
    Thorne
    4.6
    60 ct

    $0.48/ct

    $29.00 total