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    Spirulina

    With meals

    Spirulina is a blue-green microalgae (cyanobacterium) that has been consumed as a nutrient-dense food source for centuries. It is exceptionally rich in protein, B vitamins, iron, and phycocyanin — the pigment responsible for its deep blue-green color. Spirulina is widely studied for its effects on blood lipids, antioxidant capacity, and allergic responses.

    Research Evidence
    Alleviates symptoms of allergic rhinitis
    Moderate
    May reduce exercise-induced fatigue during endurance activity
    Limited
    Lowers LDL cholesterol in overweight individuals
    Moderate
    Reduces total cholesterol and triglycerides
    Strong
    May improve fasting blood glucose levels
    Limited
    Provides antioxidant and anti-inflammatory effects
    Moderate

    Expert Evidence

    3 references from 2 experts

    Currently takes

    “Personally, I do use spirulina to color my sleep supplement. Maybe there are potential additional benefits by using it as a colorant, but I don't plan on taking separate spirulina supplements at present.”

    Spirulina “Significantly Improves Weight" in New Study

    6:11
    Brad Stanfield

    2 references in 1 episode from 2025

    AI-generated summary

    Stanfield uses spirulina only as a colorant in his sleep supplement and does not take it as a standalone supplement. He cites research suggesting 2-3 grams daily of powdered spirulina for at least 7-8 weeks may improve metabolic metrics in overweight individuals. No cautions or concerns were discussed.

    Discusses

    “Both cases saw significant decreases in nasal obstruction, improved ability to smell, improved sleep, daily working inflammatory cytokines were reduced as well, reduction in nasal itching, all after taking two grams of spirulina.”

    Unknown Title

    1:45:27
    Andrew Huberman

    1 reference in 1 episode from 2021

    AI-generated summary

    Huberman cites clinical evidence that 2 grams of spirulina reduced nasal obstruction, itching, and inflammatory cytokines while improving smell and sleep. He does not mention personal use, specific dosing guidance beyond the 2g figure from the study, or any cautions.

    2025
    Safety & Cautions

    Side Effects

    • Mild digestive discomfort
    • Nausea at higher doses
    • Potential allergic reaction in sensitive individuals
    • Possible contamination with microcystins if sourced from unregulated producers
    Spirulina is generally well-tolerated at standard doses. However, sourcing matters — purchase only from reputable brands that test for heavy metals and microcystin contamination, and individuals with autoimmune conditions should consult a healthcare provider before use due to its immune-modulating properties.
    Pairs Well With
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