Digestive Enzymes
Digestive enzymes are a group of proteins — primarily protease, lipase, and amylase — that catalyze the breakdown of macronutrients into absorbable molecules. They are naturally produced by the pancreas, stomach, and small intestine, but can be supplemented to support digestion when endogenous production is insufficient. Supplemental forms are typically derived from animal pancreas (pancreatin) or fungal/plant sources like bromelain and papain.
Expert Evidence
1 reference from 1 expert

“I take a couple digestive enzymes when I eat.”
Andrew Huberman's Longevity Routine (supplements, diet, peptides, and exercise regimen)
9:221 reference in 1 episode from 2024
Huberman mentions taking digestive enzymes with meals but provides no specific brand, dosage, or timing details. No benefits, mechanisms, or cautions are discussed — this is a brief mention of personal use only.
Side Effects
- Nausea at high doses
- Abdominal cramping
- Diarrhea
- Allergic reactions in those sensitive to porcine or fungal sources
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$13.99 total
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$50.35 total