Glycine + NAC
Glycine and N-acetyl cysteine (NAC) are two amino acids that together provide the essential building blocks for glutathione, the body's primary endogenous antioxidant. Glutathione production naturally declines with aging, particularly after midlife, and supplementing with its direct precursors can help restore levels more effectively than taking glutathione itself, which is poorly absorbed orally. This combination has emerged from clinical research on aging biology and is increasingly studied for its effects on oxidative stress and mitochondrial health.
Expert Evidence
2 references from 1 expert
“When we age, a powerful antioxidant called glutathione appears to rapidly decline from the age of 45. By supplementing with the building blocks of glutathione, NAC and glycine, we can help support our glutathione levels and support mitochondrial function.”
Popular Supplements You Should NEVER Take
2:282 references in 2 episodes from 2024
Stanfield highlights that glutathione declines rapidly from age 45 and recommends supplementing with its building blocks, glycine and NAC, to restore glutathione levels and support mitochondrial function. He cites a small 2022 study showing significant mitochondrial health improvements in older adults taking the combination. No personal use is mentioned, no specific dosing is provided, and no cautions are discussed.
Side Effects
- Nausea or GI discomfort from NAC
- Sulfurous taste or smell from NAC
- Mild bloating at higher doses
- Rare headache
$0.55/ct
$32.95 total
$0.50/ct
$45.00 total