Grape Seed Extract
Grape seed extract is derived from the seeds of Vitis vinifera (wine grapes) and is one of the richest dietary sources of proanthocyanidins, a class of polyphenolic compounds. It has been widely studied for its cardiovascular-protective properties, particularly its ability to support healthy blood pressure and vascular function. The extract is commonly standardized to contain 90-95% proanthocyanidins.
Expert Evidence
2 references from 1 expert
“I take 400 to 800 milligrams of grape seed extract, usually with a meal. It's just part of my standard supplementation stack every single day, mainly for its effects on vascular function and blood flow.”
AMA #12: Thoughts on Longevity Supplements (Resveratrol, NR, NMN, Etc.) & How to Improve Memory
3:452 references in 2 episodes from 2021–2023
Huberman takes 400-800mg of grape seed extract daily with a meal as part of his standard supplementation stack, primarily for its effects on vascular function and blood flow. He lists it among his core daily supplements. No cautions, cycling protocols, or specific brand recommendations are discussed.
Side Effects
- Mild nausea
- Headache
- Dizziness
- Stomach upset in sensitive individuals
$0.07/ct
$17.89 total
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$19.95 total
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$26.69 total
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$26.25 total